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Kaplan Qbank USMLE



Author4 Posts
  #1

Many therapeutic drugs are enzyme inhibitors. Malonate is an effective inhibitor of succinic dehydrogenase because it

A. reacts with a metal ion cofactor.

B. displaces the FAD bound to the enzyme.

C. binds irreversibly to the active site.

D. covalently modifies the enzyme.

E. resembles succinate but can not undergo dehydrogenation


  #2

E- malonate is a competitive inhibitor for the enzyme.


  #3

what is the use of this malonate ?!?

  #4

Malonate is a competitive succinate dehydrogenase (SDH; EC 1.3.99.1) inhibitor but I tried to find aditional information but was unsuccessful.







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