drpkaur
Forum Guru
Topics: 196
Posts: 810
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In pts with emphysema due to alfa1 antitrypsin deficiency.the molecular mechanism responsible for the accumulation for the accumulation of alfa1 antirypsin in hepatocytes is??
A.Excessive hepatic synthesis of alfa1 antitrypsin
B.Retention in the endoplasmic reticulum cuz of poorly folded alfa1 antitrypsin.
C.Decreased catabolism of alfa-1 antitrypsin in lysosomes
D.Inability to metabolize alfa 1 antitrypsin
E.impaired dissociation from chaperones
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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B
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| fox
Forum Guru
Topics: 70
Posts: 727
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B
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