meg
Forum Guru
Topics: 62
Posts: 806
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A 29-year-old obese female comes to see you with progressive hirsutism, pustular acne, and increasing irregularity in her menses. Which of the following medications could be used to counter some of the effects of her excessive testosterone levels?
A. Finasteride
B. Fluconazole
C. Hydrochlorothiazide
D. Leuprolide
E. Spironolactone
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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i think its E
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| meg
Forum Guru
Topics: 62
Posts: 806
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terrific! you are right  Spironolactone has anti androgenic effects
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| leftfoot
Forum Elite
Topics: 29
Posts: 216
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yup! spironolactome is an aldosterone AND ANDROGEN RECEPTOR BLOCKER!
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| leftfoot
Forum Elite
Topics: 29
Posts: 216
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HEY GUYS...
finesteride and leuprolide are also androgen antagonista...how do you spironolactone above them...? :?
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| deepshikha
Forum Newbie
Topics: 1
Posts: 10
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finasteride is more of an androgen antagonist than spironolactone....finasteride is a 5alpha reductase blocker..prevents formation of testosterone while spironolactone is a receptor blocker..
this is a tough question as they have given both choices..pls someone suggest which shud be correct..
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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because finasteride is teratogenic
check this out
http://www.cushings-help.com/hirsuitism-treatment.htm
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