how many ATPs per glucose metabolism?

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how many ATPs per glucose metabolism?

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3 Posts

marine
Forum Newbie

Topics: 3
Posts: 9

09/08/06 - 02:18 AM

First Aids says 38 ATP (through malate shuttle ) or 36ATP (through G3P shuttle) are produced in aerobic glucose metabolism.

Lecture note says 8 ATP (through malate shuttle ) or 6ATP (through G3P shuttle) are produced in aerobic glycolysis.

I can't fugure out where the difference comes from. Can some one help? thanks

drpkaur
Forum Guru
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Topics: 195
Posts: 808

09/08/06 - 09:53 AM

hi marine in FA they are talking abt the complete oxidation of glucose starting from glycolysis..see in glycolytic pathway net generation of ATP'S =8(through malate shuttle)
generation of ATP in pyruvate dehydrogenation=6
generation of ATP in TCA Cycle= 24
So total net generation of ATP from one glucose molecule=38...
hope it helps...

marine
Forum Newbie

Topics: 3
Posts: 9

09/08/06 - 08:41 PM

Thanks drpkaur,

your answer was exactly what i needed! I was not counting ATP from pyruvate dehydrogenation.

now how do I come up with 12 from TCA cycle?
the following is generated per Acetyl CoA:

3 NADH
1FADH2
2COs
1 GTP

am I right and calculating:
3x3(NADH) + 1x2(FADH2) + 1(GTP)=12 per Acetyl CoA?

maybe I shouldn't get too caught up in details...

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