zubr
Forum Junior
Topics: 14
Posts: 61
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Will a sodium-channel blocker stop Na-leak into a cell?
Otherwise, a cell has working ungated potassium channels, they will hyperpolarize the membrane. The 3Na/2K/ATP pump creates out-flow of the 1 positive charge from the cell that also hyperpolarize the membrane. If it is no sodium leak the resting membrane with added sodium-channel blocker have to hyperpolarize.
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| Leopard
Forum Guru
Topics: 30
Posts: 401
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Which cell and which influx you are talking about?? Na enters slightly into every body cell through "ungated channels " and these are not blocked by "Na-channel blockers" which act only on "gated channels".
Please elaborate your question
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| zubr
Forum Junior
Topics: 14
Posts: 61
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Every cell has Na-gated channels but NO Na "ungated channels "
ONLY K has gated and ungated channels.
My question if Na leaks into a cell due to a leakage in Na-gated channels OR 3Na/2K/ATP pump?
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