DIRURESIS AND URINE OSMOLARITY

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Physiology Forum

DIRURESIS AND URINE OSMOLARITY

Author

5 Posts

Leopard
Forum Guru
avatar

Topics: 30
Posts: 401

09/06/06 - 03:53 PM

What happens to the Corticomdullary osmotic gradient with chronic use of Loop diuretics.??

___________________
FA is just a good revision book.It is not a "real" learning tool.

blueocean
Forum Senior
avatar

Topics: 15
Posts: 195

09/06/06 - 04:58 PM

decreases

Leopard
Forum Guru
avatar

Topics: 30
Posts: 401

09/06/06 - 05:05 PM

Good Blue ocean But

Can you explain Why??

___________________
FA is just a good revision book.It is not a "real" learning tool.

Lim
Forum Elite
avatar

Topics: 62
Posts: 210

09/07/06 - 12:53 AM

Furosemide ;

inhibits the active absorption of Na,K,Cl in the think ascending limb -> deplete the medullary gradient. so maybe 25% of filtered Sodium just pass...so gradient down...

(i think you need something more..than this)

___________________
The secret is never give up

elisamik
Forum Senior

Topics: 2
Posts: 39

09/15/06 - 02:15 PM

i think that loop diuretics also increase the blood flow in the vasa recta -> overflooding the loop system -> decreases the osmotic gradient

You don't have permission to post.