Leopard
Forum Guru
Topics: 30
Posts: 401
|
Enzyme Glucose 6 phosphate phosphatase located in the cells
- mitochondria
- ER
- Nucleus
- cytoplasm
- ribosome
___________________
FA is just a good revision book.It is not a "real" learning tool.
|
| drfax
Forum Elite
Topics: 21
Posts: 233
|
4.cytoplasm
___________________
My best friends are these Gentlemen :Why & How.
|
| star1
Forum Guru
Topics: 93
Posts: 827
|
ER
|
| blueocean
Forum Senior
Topics: 15
Posts: 195
|
4- cytosol
|
| docsrinu
Forum Elite
Topics: 26
Posts: 213
|
i am sure its in ER.
|
| rubensssss
Forum Guru
Topics: 95
Posts: 451
|
Cytosol
___________________
Ruben sssss
|
| Leopard
Forum Guru
Topics: 30
Posts: 401
|
Correct answer is ER
___________________
FA is just a good revision book.It is not a "real" learning tool.
|
| vijay vegesna
Forum Newbie
Topics: 1
Posts: 17
|
the answer is cytoplasm. this is an enzyme in gluconeogenesis.OAA that is syntesised in the mitochondria enters cytoplasm through malate shuttle and through series of steps form glucose in the cytoplasm
|
| new_n_lost
Forum Hero
Topics: 663
Posts: 6,106
|
Buddy can u Explain ur answer which enzyme r u talking abt G6PD or G6P ??
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| new_n_lost
Forum Hero
Topics: 663
Posts: 6,106
|
This Enzyme is specifically related to Type Ia Von Gierke's disease this enzyme is in the ER. Type I glycogen storage disease is attributed to lack of glucose-6-phosphatase. However, this enzyme is localized on the cisternal surface of the endoplasmic reticulum (ER); in order to gain access to the phosphatase, glucose-6-phosphate must pass through a specific translocase in the ER membrane. Mutation of either the phosphatase or the translocase makes transfer of liver glycogen to the blood a very limited process. Thus, mutation of either gene leads to symptoms associated with von Gierke's disease, which occurs at a rate of about 1 in 200,000 people.
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| keepgoing
Forum Fanatic
Topics: 72
Posts: 1,949
|
yes agreed ER on tissue need ---signalling---er--->g6p. normally we dont find it in cytoplasm...!
___________________
"Deh Shiva Var Mohe Ahey ,Shubh Karman Te Kabhun Na Tarun ,Na Darun Arson Jab Jaye Laroon, Nischey Kar Apni Jeet Karoon"
|
| indidoc1
Forum Guru
Topics: 50
Posts: 978
|
yup.. G6Pase is definitely in ER.. n deficient in von gierke's
___________________
"Whether you think you can or whether you think you can't, you're right!" ~ Henry Ford
|
| indidoc1
Forum Guru
Topics: 50
Posts: 978
|
the pathway of gluconeogenesis simplified is this.. (Thanks to nnl)
OAA via malate shuttle-----> cytoplasm
OAA in cytoplasm----->Phosphoenolpyruvate via PEPCK
Reversal of glycolysis n fructose 1,6 bis Phosphatase ------> Glucose 6 phosphate in cytoplasm.
Glucose 6 phosphate-------> ER via translocase
Inside ER, gucose 6 Pase acts on it -------> Glucose
___________________
"Whether you think you can or whether you think you can't, you're right!" ~ Henry Ford
|
|
| |
| | | | | | | | | | | | | |
