half life

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half life

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meg
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Topics: 62
Posts: 806

01/28/04 - 12:34 PM

The half-life of a drug is longest in which situation?

A. A small volume of distribution

B. A large volume of distribution

C. A high concentration of drug in the plasma

D. Low concentrations of the drug in organs and tissues

E. Less total drug is present

F. An oral drug is given more frequently

G. An oral drug is given in higher doses

asmi
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Topics: 1043
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01/28/04 - 02:48 PM

i think C

alice8
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01/28/04 - 02:50 PM

B. A large volume of distribution :?:

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mahendra
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01/28/04 - 02:56 PM

I THINK C

mjl1717
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01/28/04 - 07:00 PM

answer -b (large vol. of distribution)

t1/2=0.693 times Vss/Cl :idea:

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ramo7
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Topics: 15
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01/29/04 - 01:40 AM

half life of a crug is only dependent on the volume of distribution so the answer is B

meg
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Topics: 62
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01/29/04 - 10:08 AM

B is right
mjl1717 gave the formula

asmi
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Topics: 1043
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01/29/04 - 11:23 AM

thanks

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