meg
Forum Guru
Topics: 62
Posts: 806
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A 52-year-old woman is referred to your gynecology office with complaints of hot flashes and insomnia associated with menopause. She has a history of hepatitis B, hypertension, osteoporosis, chronic obstructive pulmonary disease, and hyperthyroidism. Of all her present conditions, which represents the only absolute contraindication to estrogen-based hormone replacement therapy?
A. Chronic obstructive pulmonary disease
B. Hepatitis B
C. Hypertension
D. Hyperthyroidism
E. Osteoporosis
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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its C
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| deepshikha
Forum Newbie
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its b..hepatitis..estrogen is contraindicated in liver diseases..
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| leftfoot
Forum Elite
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Posts: 216
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i agree..its B.
liver disease is a contraindication for estrogen...estrogen worsens it and causes cholestasis.
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| asmi
Forum Hero
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yes i think that you guys are right
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| alice8
Forum Guru
Topics: 37
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Meg mentioned only she has a history of hepatitis,there is no clue about her hepatitis if she is Anti HBs positive or not...if so ,that means she has no risk for carrier or progression to chronical stage of disease...
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| step1taker
Forum Senior
Topics: 2
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I believe the answer is B. 
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| meg
Forum Guru
Topics: 62
Posts: 806
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yes, B is the right answer.
I had chosen hypertension initially and was wondering how hepatitis B could be contraindication, but your answers have thrown light on hepatitis (cholestasis). Thanks.
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