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drpkaur
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09/02/06 - 04:18 PM             #1

which of the following drug is called as suicide inhibitor???
1.methotrexate
2.trimethoprim
3.5-FU
4.Sulphonamides
5.hydroxyurea

Cedrick
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09/02/06 - 04:19 PM             #2

3 ?

drpkaur
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09/06/06 - 11:35 AM             #3

correct it's C....-5-FU...
NOBODY is participating these days.....

aisha2
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09/06/06 - 02:58 PM             #4

i knew the answer , but can some one plz explain this , why is it call the suiccide inhibitor

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docsrinu
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09/06/06 - 08:08 PM             #5

5-FU is converted to 5-FdUMP by thymiylate synthase and 5-FdUMP inhibits the enzyme.







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