docarchana
Forum Guru
Topics: 70
Posts: 515
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r platelets granulocytic? does GMCSF have a role in their production?
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| Ivil
Forum Senior
Topics: 8
Posts: 169
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platelets r derived from megakaryocytes which is one of the myeloid stem cell lineage..
GM-CSF & IL 3 -differentiation of pleuripotent cells to myeloid stem cell
IL 7 -differentiation of pleuripotent cells to lymphoid stem cell
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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thanku Ivil. So GMCSF has role in platelet production. btw r platelets classified under granulocytes like neutrophils?
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| waqastariq
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no they arent 
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| vallia
Forum Guru
Topics: 98
Posts: 889
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no, plateles are derived from megakaryocyte.
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| vallia
Forum Guru
Topics: 98
Posts: 889
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the big one is megakaryocyte. evolution from pluripotent stem cell--->megakarioblast---->promegakaryocyte---->megakariocyte----f ragmented---platelets in blood.
Attached Files:
megakaryocytes, erytroid precursors,granulocytic precursors, normal.jpg (65 KB, 6 downloads)
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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thanx guys
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