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Kaplan Qbank USMLE



Author6 Posts
  #1

CSF examination for meningococcemia

  #2

agreed...

DIC due to meningococcemia.


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  #3

actually id just focus on DIC...can occur coz of any infection.

in the coagulation tests, both PT and Aptt will be prolonged.

and confirmatory test wud be FDPs eg d - dimer

wif we had a istrory of PC compatible with meningitis, then id look for them in the CSF.


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  #4

yes i agree the tests would be coagulation tests and fdp dimers. next would be to find out what organism is causing the septicemia.

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  #5

to confirm you need a blood culture, but itīll take some time

  #6

studyin u r right..
this is the case of acute DIC..which is associated with G+ and G- septicemia,typhoid fever,rochy mountain spotted fever,viremia and parasites
DIC in simplest terms a loss of balance b/w clot forming activity of thrombin and clot lysing(fibrinolysis) results from plasmin formation,and the pt presents with hemmorrhagic state.DIC usually is associated with a high mortality rate becuz of underlying disease.morbidity associated with DIC results from vascular thrombosis,acral cyanosis,and limb ischemia.
screening tests measure(PT),(aPTT), PLATELET COUNT AND FIBRINOGEN LEVEL.
confirmatory D-dimer test detects plasmin cleaved,insoluble,cross linked fibrin.FDPS only measure plasmin-cleaved fibrinogen or fibrin.

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