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Kaplan Qbank USMLE



Author6 Posts
  #1

A series of experiments is performed to determine the mechanism by
which a pharmacologic agent tranverses cell membranes and accumulates
within target cells. The rate of transport depends on the concentration of
the durg only. When the extracellular concentration of the agent exceeds
10mM, no further increase i the rate of uptake is oberved. Structurally
similar compounds pass through the cell membrane, but at a lower rate.
Ouabain, an inhibitor of Na/K ATPase fails to inhibit transport. Which
of the follwoing is the mostl likely mechanism by which this agent
enters cells?

a. antiport
b. facilitated diffusion
c. ion gated coupling
d. simple diffusion
e. symport


  #2

b?

  #3

B is the answer


  #4

B-facilitated diffusion needs only a carrrier not the energy provided by Na/k-ATPase which is needed for primary and secondary active transport.Correct me if am wrong please.

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Never underestimate the power of prayer.

  #5

B...i think. As the carrier is saturated, the rate of diffusion plateaus off...that's my educated guess!

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Aim High

  #6

i also think, it is facilitated diff

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saif







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