Cedrick
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What is the mecanism of methemoglobin ?
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| icemaiden
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combines with CN- and forms cyanmethmoglobin and then when treated with Na thiosulphate,forms thiocyanate .
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| Cedrick
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thanks of the quick reply
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| ssrpk
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- CN has very high affinity for the iron present in ETC complex IV (cytochrome oxidase).
- Methemoglobin with its oxidized iron (Fe+3) captures this bound CN- and forms cyanmethemoglobin, which later on can be detoxified by a sulphur donor, thiosulphate, as icemaiden has mentioned.
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| Cedrick
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| Cedrick
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