Cedrick
Forum Fanatic
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Peptide bond
a.-has partial double-bond character
b.-is ionized at physiologic pH
c.-is cleaved by agents that denature proteins,such as organic solvents and high concentrations of urea
d.-is stable to heating is strong acids
e.-occurs most commonly in the the cis configuration
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| drpkaur
Forum Guru
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a is correct i think..
peptide bond is uncharged and polar...not cleaved by denaturing agents,only prolonged exposure leads to its hydrolysis and lastly it occurs in trans configuration....
am i right...
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| Cedrick
Forum Fanatic
Topics: 322
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yes you are correct
and thanks for the brief explanation
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| Cedrick
Forum Fanatic
Topics: 322
Posts: 1,990
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A
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| Cedrick
Forum Fanatic
Topics: 322
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| muzammil
Forum Guru
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gud explnation pkaur
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| ManuNastai
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It's a very complicated explination
2 electrons tend to migrate from the Nitrogen's outer orbitals to the former single bond between N and C of the peptide bond and 2 e- from the double bond C=O tend to move in the outer orbitals of O making it O-. So, the peptide bod is always shifting from double to single bond, making it not a single, nor a double, but a partially double bond.
It was very chalenging to try to explain this...
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