MRMAVERICK
Forum Guru
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A 58-year-old male has diabetes mellitus. This disease
has been poorly controlled for many years. As a conse-
quence, he has had nonenzymatic glycosylation of free
amino groups of proteins in his body. This process is best
illustrated by finding which of the following pathologic
abnormalities?
O (A) Peripheral neuropathy
O (B) Amyloid replacement of islets
O (C) Formation of retinal microaneurysms
O (D) Accelerated atherogenesis
O (E) Cataracts
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| star1
Forum Guru
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(C) Formation of retinal microaneurysms
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| fox
Forum Guru
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I think its A
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| PatriciaLim
Forum Senior
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i think A too.
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| sosikan
Forum Junior
Topics: 3
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why not c could you explain why you choose a?
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| sridevibandaru24
Forum Guru
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the answer is D
(it is given in Goljan's pathology review pg 262..........glucose comines with aminogroups of proteins which forms advanced glycosylation end products (AGEs) that alter vessel permeability and increse atherogenesis) options A,C and E are due to osmotic damage.
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| fox
Forum Guru
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Thanks for clarifying Sridevi
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