drpkaur
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A 70 yr man complains of urinary frequency, diminished force of his stream, inability to empty his bladder completely, and nocturia of four or five times. On rectal examination, the prostate is enlarged, smooth, symmetric, and nontender. The androgen most responsible for his prostate enlargement is
(A) testosterone
(B) dihydrotestosterone
(C) dehydroepiandrosterone
(D) androstenedione
(E) aldosterone
187. On further questioning, the patient reports frequent episodes of allergic rhinitis for which he takes large amounts of self-prescribed medication containing phenylpropanolamine. His symptoms of bladder neck outlet obstruction may be wors- ened by this drug because of its
(A) anticholinergic activity
(B) cholinergic activity
(C) sympathetic α-blocking properties
(D) sympathetic α-agonistic properties
(E) sympathetic β-agonistic properties
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| icemaiden
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B & D
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| young_doc
Forum Guru
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yes, B/D.
The hormone responsible for Prostate enlargment is DHT. (and NOT Testosterone)
And the urinary sphincter is contracted by alpha-1 agonization. (Or if you knew your pharm cold, you would know that Phenylpropanolamine is an alpha1-agonist. Or even if you didn't know that, you could guess that an OTC drug taken for nasal congestion could be an alpha1-agonist!!!!!)
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| drpkaur
Forum Guru
Topics: 195
Posts: 808
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yes B and D are correct...
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