Lim
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The data shown in the table below were collected from a 21-year-old college football player involved in a clinical study.
inulin space 20L
Blood volume 7L
Plasma volume 4L
Plasma osmolarity 285mOsm/L
Body weight 100Kg
What is the approximate interstitial fluid volume?
A. 9L
B. 13L
C. 16L
D. 40L
E, cannot be determined
VAS(vascular component) includes plasma voulme and red blood cells(blood volume)?
thanks in advance.
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| young_doc
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13?
I'm guessing it's simply (ECF) - (Blood Volume), or 20-7
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| Lim
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sorry but wrong..hm...
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| docarchana
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16? ECF - PLASMA.
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| Lim
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yes,you're right,docarchana.
VAS includes Blood volume? could you explain,please?
in kaplan physiology
VF : approximately 1/3 of the ECF(plasma plus red blood cells). A normal vascular volume is close to 5L(blood volume)
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| charu78
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Isnt Interstial fluid 2/3rd of ECF and in that case, shouldnt the ans be 13[b].
i am sorry i am not quite sure how u worked the calculation, can u please explain, docarchana and lim
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| young_doc
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Why is it ECF - Plasma... how then do you account for the RBC's? Why not substract the total volume taken up by the blood (i.e Blood volume).
Plz explain 
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| Ivil
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Fluid in RBC will be IntraCellular fluid rather than Interstitial Fluid. So you dont take total blood volume into account...
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| young_doc
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wow...haha. I dont know how that one flew right past me at first. THANKS IVIL!!!
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| smalldoc
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body weight is 100 kg,60 % is t total body water which is 60 L
1/3rd total body water is ECF,corresponding to inulin space.
ECF is interstitial fluid + plasma volume(blood volume is plasma + cells)
cells dont count as part of t ECF(as t name goes)
hence
interstitial fluid is 16
right?
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| proctalgia
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Intracellular fluid( ICF )= 2/3 of body water.
Extracellular ( ECF ) = 1/3 of body water.
ECF = ISF (Interstitial fluid ) + Vascular fluid (VAS -Plasma+rbc)
In the ECF 2/3 is ISF and 1/3 is VAS.
Here VAS =7L ----->1/3 of ECF. So the other 2/3 is ISF. In this case ISF must be close to 14.
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| Addicudo
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HMm Proctalgia .. Your are right partly ... except at one place .. This is a Failry smiple one ... ECF = Blood Plasma Volume (WITHOUT RBC) + Interstitial Fluid (Fluid b/w Cells) Therefore according to the Question .. ECF = 20 Plasma Volume = 4 Liters .. 20 - 4 = ICF Answer is C
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