fongch
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Over a month period, a 35-year-old man develops symptoms of hyperthyroidism with tachycardia and heat intolerance. Thyroid biopsy demonstrates a heavy mononuclear cell infiltrate with multinucleated giant cells, follicular disruption and loss of colloid. About one month later, the patient develops symptoms of hypothyroidism. To which of the following is this patient's condition thought to be most closely related?
A. Blocking TSH receptor autoantibodies
B. Carcinoma
C. Lymphoma
D. Stimulating TSH receptor autoantibodies
E. Viral infection
This is a question from Kaplan Step 1 Qbank.
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| sridevibandaru24
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i think it is hashimotos as the features are first of hyperthyroidism followed by hypothyroidism. so the answer is A
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| icemaiden
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c?
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| fongch
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Personally I agree with you guys that this is a case of Hashimoto thyroiditis, thus the answer must be between A and C. However, according to the explanation provided by Kapland, this is a case of subacute thyroiditis, and their answer is E.
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| icemaiden
Forum Elite
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Oh! yeah right -----the multinucleted giant cell!!Dint pay attention to that!
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| fongch
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But will subacute thyroiditis ends up in hypothyroidism?
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| icemaiden
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yeah it does. It has a triphasic course ----hyperthyroidism,hypothyroidism and finally normal thyroid function.The hypothyroidism is usually mild and may not require treatment
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| MRMAVERICK
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ya e
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