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Kaplan Qbank USMLE



Author3 Posts
  #1

Can anyone define type III hypersensitivity reaction and give 10 examples?

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Smell the coffee! "Is That an Osler move??"

  #2

10? TYpe III hypersensitivity is an immune complex reaction against an antigen that stimulates the complement cascade, by settling in vessels, on membranes, or in ducts. Often, type III is IgM mediated.

SLE is the most famous example
Type I and II MPGN
Mycoplasma pneumonia, infectious mono, and chlamydia can all cause autoimmune hemolytic anemia that are type III, as can isoniazid

all i got right now

  #3

*(AgAb)complexes on the target tissue :arrow:--- activate complement and neutrophils/macrophages do damage (think G.N. and vasculitis)

add Farmers lung (arthus rxn)
Serum sickness
Rheumatoid Arthritis
Polyarteritis Nodosa
Extrinsic Allergic pneumonia
Poststreptococcal Glomerulonephritis
HIV :idea:

By the way I DISAGREE with your autoimmune hemolytic anemia!
perhaps you are referring to Arthus rxn or Serum sickness

___________________
Smell the coffee! "Is That an Osler move??"







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