sridevibandaru24
Forum Guru
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23 year old female comes with a 1 week h/o a nontender papule on her vulva and inguinal lymphadenopathy. vdrl is positive, elisa for hiv is negative. patient is treated with an injection of benzathine penicillin. later in the evening she develops fever, headache, chills, muscle pain. blood cultures are negative.bp is 90/60 hr is 100/min. which of the foll actions is appropriate?
a. stop benzathine penicillin
b. decrease the dose of benzathine penicillin
c. stop benzathine penicillin and treat with steroids
d. treat with same dose of benzathine penicillin
e. double the dose of benzathine penicillin
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| mousa
Forum Senior
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d
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| mousa
Forum Senior
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Posts: 64
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THIS COMPLICATION OF SYPHILIS TREATMENT
Jarish-Herxheimer reaction: start general during 24 hrs of antibiotics therapy ,increase T,decrease BP,rigors,leukopenia
this occuring during treatment any of the spirochete disease
I WISH I AM RIGHT.
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| mousa
Forum Senior
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SO I THINK IT IS NORMAL COMPLICATION FOR SYPHILIS TREATMENT ...SO JUST CONTINUE THE SAME DOSE......D
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| Dragonfly
Forum Elite
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but how can we differentiate this from Penicilline Allergy in which WE MUST STOP??
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| docarchana
Forum Guru
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sridevi, wats the correct ans?????/
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| mousa
Forum Senior
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i think if there is any allergy for pencillin ,it is started with macularpapular RASH(the most comon rash seen in pencillin allergy),ANGIOEDEMA(marked swelling of the lips,tongue,periorbital area),and anaphylaxis may be BRONCHSPASM.....so there is just fever ,decrease BP,headache which happen from the KILLED organism that realse pyrogen(fever producing enzyme)......JARISCH HERXHEIMER PHENOMEN
I WISH I AM RIGHT
SO I AM STILL WITH ..D
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| icemaiden
Forum Elite
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D.Does not describe any features of allergy/anaphylaxis
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| fox
Forum Guru
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Also penicillin allergy will manifest immediately after administration of the drug & not late in the evening. This is Jarish hex reflex no doubt, but do we have to continiue penicillin in same dosage or decrease it till patient stabilises....this Im not really sure.
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| disha
Forum Senior
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Posts: 118
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ok so its a
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| disha
Forum Senior
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Posts: 118
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sorry d
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