Unanswered NBME Pharm Questions

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Pharmacology Forum

Unanswered NBME Pharm Questions - exam in 2 weeks

Author

9 Posts

amitdoc2b
Forum Senior

Topics: 42
Posts: 97

08/16/06 - 02:58 PM

Hi guys.. these are different than my last post, I tried finding a bunch on my own but couldn't answer some.. ive posted those below..

I wanted to thank everyone who has helped me out with the NBME questions for this topic. But I still have some questions that were are unanswered and my exam is in 2 weeks! sad

Can you please help me out with them? I wanted to understand also why it is the correct answer and I have been having trouble finding the reasoning behind these particular questions.

I've attached 4 files in this topic, I have to do it in separate replies cuz it only lets me attach one file at a time..

Thanks!!

Attached Files:
pharm_1.JPG (125 KB, 62 downloads)

amitdoc2b
Forum Senior

Topics: 42
Posts: 97

08/16/06 - 02:59 PM

here's the 2nd file..

Attached Files:
pharm_2.JPG (150 KB, 42 downloads)

amitdoc2b
Forum Senior

Topics: 42
Posts: 97

08/16/06 - 02:59 PM

here's the 3rd..

Attached Files:
pharm_3.JPG (122 KB, 36 downloads)

amitdoc2b
Forum Senior

Topics: 42
Posts: 97

08/16/06 - 02:59 PM

here's the 4th and final file...

Attached Files:
pharm_4.JPG (65 KB, 35 downloads)

study_ing
Forum Fanatic
avatar

Topics: 180
Posts: 2,509

08/16/06 - 05:22 PM

14 is B probably. the patient has anticholinergic symptoms and diphernhydramine has antich side effects.

41 is E. remember the incidence of fatal side effects is very low. if it were not, they wudnt be used. if a drug has a sideffect 1 in 100, 000 for example, chanes of it being detected in sudies with sample size in thousands are pretty low.

___________________
If you yourself are at peace, then there is at least some peace in the world.

study_ing
Forum Fanatic
avatar

Topics: 180
Posts: 2,509

08/16/06 - 05:26 PM

1. antihyperlipidemic with the side effect of flushing wud be niacin

24. i think omeprazole, a ppi wud be most effective in this case.

___________________
If you yourself are at peace, then there is at least some peace in the world.

amitdoc2b
Forum Senior

Topics: 42
Posts: 97

08/17/06 - 07:52 PM

thanx study_ing....can anyone help on the rest of the questions??

Dragonfly
Forum Elite
avatar

Topics: 27
Posts: 338

08/18/06 - 01:01 AM

WOW, these are a lot grin

3. A. cocain, inhibits reuptake of nuerogenic amine :NE, DA, etc.

also TCA uses the same mechanism

18. C. ACE-I are teratogenic. contraindicated in pregnancy

23.D. it closes the sarcoplasmic Ca channels

25. ?

42. i think D. i think C. only happens to the main chromosome not to the plasmid. (correct me if i am wrong)

22. B. this is OA which unlike RA is Not an inflammation. and i think pain mangement with an NSAID is enough.

A & E are for gout.

30. B. folate deficinecy

27. D. typical antidot for B-blockers. increase cAMP

40. ?A. it is an Estrogen-receptor antagonist in the breast and uterus but an agonist in the bone

1. A. Niacin. dec, VLDL, LDL but increases HLD !! the cutanous flushing can be pretreated iwth NSAIDS and tolerance develops withtin days. (agree with study_ing)

22. B. great biavalability and tissue absorption

the rest are NOT even absorable orally !!! you can eliminate them right away

24. D. PPIs block IRREVERSIBLY the same H-K pump that Gastrin activates. this is Zollinger-Ellison(agree with studyin_ing)

30. most probably A. it is B-agonist which acts like Epi. G. is very commonly given for this but it is worthless. b/c tolerance develops within days !!

50. E. all true for theophylline

14. B. this is a 1st generation anti-histamine with lots of side effects,most impotantly M & Alpha blocking and sedation. (agree with study_ing)

these symptoms are due to M block like atropin.

41. i think E. same reason as study_ing

hope it helped.

___________________

amitdoc2b
Forum Senior

Topics: 42
Posts: 97

08/18/06 - 04:28 AM

Dragonfly wrote:
WOW, these are a lot grin

3. A. cocain, inhibits reuptake of nuerogenic amine :NE, DA, etc.

also TCA uses the same mechanism

18. C. ACE-I are teratogenic. contraindicated in pregnancy

23.D. it closes the sarcoplasmic Ca channels

25. ?

42. i think D. i think C. only happens to the main chromosome not to the plasmid. (correct me if i am wrong)

yes this helped a lot, thank u! hopefully u didnt do the NBME tests, u probably have gone thru them on the board here anyways!! hehe... thanks so much again.

22. B. this is OA which unlike RA is Not an inflammation. and i think pain mangement with an NSAID is enough.

A & E are for gout.

30. B. folate deficinecy

27. D. typical antidot for B-blockers. increase cAMP

40. ?A. it is an Estrogen-receptor antagonist in the breast and uterus but an agonist in the bone

1. A. Niacin. dec, VLDL, LDL but increases HLD !! the cutanous flushing can be pretreated iwth NSAIDS and tolerance develops withtin days. (agree with study_ing)

22. B. great biavalability and tissue absorption

the rest are NOT even absorable orally !!! you can eliminate them right away

24. D. PPIs block IRREVERSIBLY the same H-K pump that Gastrin activates. this is Zollinger-Ellison(agree with studyin_ing)

30. most probably A. it is B-agonist which acts like Epi. G. is very commonly given for this but it is worthless. b/c tolerance develops within days !!

50. E. all true for theophylline

14. B. this is a 1st generation anti-histamine with lots of side effects,most impotantly M & Alpha blocking and sedation. (agree with study_ing)

these symptoms are due to M block like atropin.

41. i think E. same reason as study_ing

hope it helped.

You don't have permission to post.