Perhaps
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A 4-month-old boy is brought to the physician because of a 2-day history of fever and progressive redness around his right eye. He has had persistent diarrhea and oral candidiasis since birth and was treated for pneumococcal pneumonia at the age of 2 months. He appears ill. His temperature is 39 C (102.2 F), pulse is 130/min, and respirations are 25/min. Examination shows violaceous preseptal (periorbital) cellulitis and oral candidiasis. Laboratory studies show:
Hemoglobin 10 g/dL
Leukocyte count 3000/mm3
Segmented neutrophils 85%
Lymphocytes 15%
Platelet count 350,000/mm3
Serum
IgA <5 mg/dL
IgG 300 mg/dL
IgM <5 mg/dL
Which of the following is the most likely diagnosis?
A) AIDS
B) Chronic granulomatous disease
C) Severe combined immunodeficiency
D) Thymic-parathyroid dysplasia (DiGeorge syndrome)
E) X-linked agammaglobulinemia
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| sunny2
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Please write NBME Form no. while posting your questions.
Perhaps and Structure kindly take note.
Thank you
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| djacosta
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scid
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| frank100
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severe combined immunodeficiency
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