asmi
Forum Hero
Topics: 1043
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Suppose that you have done a carrier test for PKU (autosomal recessive disorder) in a population, and you discover that the heterozygote carrier frequency is 1/500. Based on this information, what proportion of the population will be affected with PKU?
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| meg
Forum Guru
Topics: 62
Posts: 806
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2pq= 1/500
q= 1/250
q2= (1/250)2 = 1/62500
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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meg,
Here q =1/1000
so q2 = 1/1,000,000
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| meg
Forum Guru
Topics: 62
Posts: 806
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:oops: I should be careful in calculations
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