vallia
Forum Guru
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An 8 year-old girl with cistic fibrosis is treated with ciprofloxacin for a pseudomonas aeruginosa infection in her lungs. Which of the following enzymatic activities is most directly affected by this drug?
A. the synthesys of RNA primers
B. the breaking of H bonds in front of the replication fork
C. the breaking and rejoining of DNA backbone
D. the removal of RNA primers
E. the joining togheter of Okazaki fragments
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| Musuq
Forum Guru
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I would go with C)
because Ciprofloxacin (a Quinolone) is a Topoisomerase II (DNA Gyrase) inhibitor, so, the breaking and rejoining of DNA would be involved in this inhibition, thus replication wont be possible for this bug.
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| sridevibandaru24
Forum Guru
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Posts: 434
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yeah c is correct
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