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Kaplan Qbank USMLE



Author5 Posts
  #1

I attached the question and answer choices below.. please explain this one to me as I don't understand it. Thanks very much.

  #2

oops forgot to attach.. here u go...

Attached Files:
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  #3

the question describes a blistering disorer most likely pemphigus. hence i wud choose b. even if idont know what disease it is, i'd think that a, c, d have little to do with intercellular adhesions which r disrupted in a blistering disorder

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  #4

B. this is pemphigus vulgaris, the problem is b/w desmosomes which are on the lateral sides of the epithelia ,connected normally by Intermediate filaments(Tonofilaments).

See Kaplan Anatomy 1st chapter.

NOTE:

Pemphigus Vulgaris = desmosome-desomsome adherence problem(b/w 2 adjacant epithelia) , more severe

Bullous Pemphigoid= desomsome-hemidesmosome adherence problem (b/w epithelia+ basement memb.), less severe



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  #5

amit from which form is this q. plz mention that in ur posts.







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