study_ing
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http://www.cdc.gov/travel/malariadrugs.htm
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| study_ing
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For the best protection against malaria, it is important to continue taking your drug as recommended after leaving the malaria-risk area (4 weeks for mefloquine, doxycycline, or chloroquine; 7 days for atovaquone/proguanil or primaquine). Otherwise, you can develop malaria. Halofantrine (also called Halfan) is widely used overseas to treat malaria. CDC recommends that you do not take Halfan because of serious heart-related side effects, including deaths
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| study_ing
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Travelers to areas with malaria risk in Africa, South America, the Indian Subcontinent, Tajikistan, Asia, and the South Pacific should take one of the following antimalarial drugs (listed alphabetically):
- atovaquone/proguanil doxycycline mefloquine primaquine (in special circumstances).
just to list the bare essentilas
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| frank100
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study_ing is right. another thing: If you are goin to the caribean, mexico or Central America, you can use chloroquine. If you are going to a chloroquine resistant area such as the old world (africa, India, south east asia), mefloquine is fair.
and important, in pregnancy; atovaquone and proguanil
all of them are profilaxis. treatment is different.
and...I donīt know if they like those questions on the USMLE, since I havenīt done it yet. but now you know it...and thatīs what makes the difference.
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| humbty
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Thanks for your replies!
BUt on the CDC page Atovaquone and proguanil is not recommended for pregnancy.
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| frank100
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ok, in that case: chloroquine and proguanil are the prefered chemoprofilactic drugs against malaria in the first 3 months of pregancy. mefloquine can be given during second and third trimesters if the sutuation demands.
If CDC says so...we must avoid it, but must use something, if we donīt want our malpractice insurance go up up up up up up...
you can make a lot of combinations, and it depends on the pregnancy stage.
all those antymalarial antibiotics have some risk of teratgenicity.
donīknow, maybe if the option that says: "let her deliver her baby first, and the go and get malaria, can be a right answer"
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| shumaila
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pregnent pts should nottake proguanil or atavuquone
vuquone
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| frank100
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so, we already know what thwy shouldnīt take...done
but: What should they take?
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| frank100
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posible answers:
1. do not get out of the US.
2. use tons of mosquito repelent.
(laughs)
ignorance is bliss, Iīm bitting my nails...HELP!!!
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| study_ing
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lemme summarize what the cdc linnk informs pregnant women abt
Pregnant women should NOT take the following antimalarial drugs:
atovaquone/proguanil, doxycycline, or primaquine.
These drugs are either not safe to take during pregnancy or we don't currently have enough information to judge their safety.
So these we definitely rule out.
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| study_ing
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Caution: Travel to a Malaria Risk-area During Pregnancy is NOT Recommended -
postpone trip -
inform pt of greater risk to pregnant ladies -
if Have to, non pharma measures ( eg prevention of mosquito bites) -
benefits of pharmacotherapy outweigh those of malaria in pregnancy -
prescribe either chloroquine or mefloquine based on resistence patterns -
Experience with chloroquine and limited experience with mefloquine indicates that they are safe to take during pregnancy, including the first trimester -
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| study_ing
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| humbty
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Great information. Thanx Study_ing
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| frank100
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so, the point is:
if a pregnant woman need to go to a malaria endemic area, she should have medical prophilaxys with either: chloroquine or mefloquine? hhum, good thanks
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