amitdoc2b
Forum Senior
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Posts: 97
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Can someone please explain the answer of this one to me, I don't understand it:
A neoplasm in the colon invades thru the basement membrane into the lamina propria. Which of the following preotins is directly involved in the process of invasion?
a) apc gene product
b) p53 protein
c) ras gene product
d) rb gene product
e) collegenase type 4
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| amitdoc2b
Forum Senior
Topics: 42
Posts: 97
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i made a typo, that should say "proteins" not "preotins"...sorry
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| study_ing
Forum Fanatic
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e. the question basically wants to know which enzyme aids in penetration of BM ...the remaining geneproducts are involved in carcinogenesis but have dif roles..eg tumor supressor, growth factor receptor..but collagenases help degradation reired for invasion
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| sridevibandaru24
Forum Guru
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E
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| tolito
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E 
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| dericanthony
Forum Newbie
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E
type IV collagen in the basement membrane -- needs collagenase to break it down
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| Dragonfly
Forum Elite
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E. this was my question in the real exam 
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| twesting2173
Forum Senior
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Posts: 65
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i think tnf beta makes collegenase. and tnf alph is for angiogenesis....right? thanks.
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