giovanni83
Forum Senior
Topics: 24
Posts: 125
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I thought too that's it was b, but I was wrong.....I read the right answer and it's not b...
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| dr_bilalahmad
Forum Newbie
Topics: 4
Posts: 18
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its b.
increasing ecf K will deacrease leakage of K from ungated K channel which will lead to depolarization.
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| giovanni83
Forum Senior
Topics: 24
Posts: 125
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K will increase excitation, but in this case it's not the one who causes THE MOST excitation...try again...
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| drpkaur
Forum Guru
Topics: 195
Posts: 808
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is it d???
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| blueocean
Forum Senior
Topics: 15
Posts: 195
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Could be D- in hypocalcemia the cells close the gates so the i.c Ca will be increased which means more + ions in cells and excitability.But maybe I am wrong...
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| proctalgia
Forum Senior
Topics: 2
Posts: 209
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i think it is A
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| mytime
Kick my butt!
Topics: 39
Posts: 3,174
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It is d...Ca...coz excitability .Increased ca...cozes Na channels to open where as K causes it to close.
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| thinkpositive
Forum Newbie
Topics: 10
Posts: 24
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A .
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| giovanni83
Forum Senior
Topics: 24
Posts: 125
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the right answer it's D, if you want I can send you the explanation too...
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| lnb6des
Forum Newbie
Topics: 0
Posts: 5
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i think it's D
because when Ca decreased the threshold need will be decreasedto the +ve direction
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| giovanni83
Forum Senior
Topics: 24
Posts: 125
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The answer is d. (Guyton, p 59.) Membrane excitability is related to
the ease with which Na+ channels open when the cell is depolarized. The
activation of Na+ channels or the opening of the m gate is governed in part
by the extracellular Ca2+ concentration. When extracellular Ca2+1 is lowered,
the m gate can open at more negative membrane potentials, and
therefore the membrane is more easily excited. Although increasing extracellular
K+ will bring the membrane closer to threshold and thus may make
it more excitable, its predominant effect is to cause the inactivation of Na+
channels by the closing of the h gates. Inactivation of sodium channels
makes the cell membrane less excitable.
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