giovanni83
Forum Senior
Topics: 24
Posts: 125
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Interference with Neural Control Mechanisms
Anything that interferes with neural function or with excitation–contraction coupling will cause muscular paralysis. Two examples are worth noting:
1. Botulism results from the consumption of contaminated canned or smoked foods that contain a toxin. The toxin, produced by bacteria, prevents the release of ACh at the synaptic terminals, leading to a potentially fatal muscular paralysis.
2. The progressive muscular paralysis of myasthenia gravis results from the loss of ACh receptors at the junctional folds. The primary cause is a misguided attack on the ACh receptors by the immune system. Genetic factors play a role in predisposing individuals to this condition
Instead tetanic toxin:
interfere with inhibitory glicine e gaba, leading to higher eccitability.
Is it right this summary??
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