giovanni83
Forum Senior
Topics: 24
Posts: 125
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why epinephrine causes hiagh heart rate and norepineprone low heart rate? If baroceptor reflex is involved with nore.,why is it not involved in ep.???
see this site for graphs
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| pseudomonas
Forum Newbie
Topics: 0
Posts: 6
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ciao Giovanni
norepinephrine works on alpha1, alpha2 and beta1 receptors. As a result it increases total peripherial resistance, systolic and diastolic blood pressure -> reflex bradycardia may ensue.
epinephrine works on aplha1, aplha2, beta1 and beat2 receptors. At low doses beta activation predominates -> TPR decreases (beta2) and HR increases (beta1). At high doses alfa activation predominates and epinephrine has similar effect to norepinephreine including reflex bradycardia.
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