rn
Forum Senior
Topics: 30
Posts: 80
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okt3 monoclonal aby-i know its immunosuppressive,can anyone explain a bit abt this plz
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| IMMuDoc
Forum Newbie
Topics: 0
Posts: 4
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late answer, but here you are
OKT3 binds to CD3 molecule on T cells, causing either anergy(without anti-CD28 signal) or T cell eradication by following mechanisms, complement-dependent cytolysis, cell-mediated antibody-dependent cytolysis.
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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OKT3 is used to block the function of Tcells which play a major role in acute graft rejection.
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