humbty
Forum Elite
Topics: 24
Posts: 135
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This question is about cerebral toxoplasmosis, which answer is correct. Kaplans answer is: life long prophylaxis is necessary.
Thats wrong in my opinion. Harrisons 16th edition writes: secondary prophylaxis can be discontinued when initial therapy has been completed, they are asymptomatic and CD4 count is above 200 for 6 months.
So dont let Kaplan fool you with that question 
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| frank100
Forum Guru
Topics: 48
Posts: 586
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not evdence base but here I go:
I did a rotarion of 3 months in infetious diseases department (AIDS), and they give toxo profilaxis for life to them in ths cases...
I would go for rest of life treatment.
I have harrisonŽs 16th edition, IŽll look for it tonight, so I can get what do they mean by saying seondary profilaxis.
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| humbty
Forum Elite
Topics: 24
Posts: 135
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Secondary prohpylaxis (Chronic maintenance therapy) means prophylaxis after true cerebral toxoplasmosis. Primary prophylaxis means prophylaxis without preceding cerebral toxo, it is instituted for patients with positive serology and CD 4 <100.
Its on page 1248 in Harrisons.
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| frank100
Forum Guru
Topics: 48
Posts: 586
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yes, I have just read it and seems youŽre right.
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| shumaila
Forum Elite
Topics: 58
Posts: 347
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just curious are u guys reading from harrison for step 2 or just solving questions from its mcq book?
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| humbty
Forum Elite
Topics: 24
Posts: 135
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I read a lot in Harrisons during my internal medicine rotations and I am now preparing for Step2ck which I have scheduled in 2 weeks. At the moment I m using the Harrisons only as reference if I do not agree with answers or explanations or if I think I should repeat a topic in depth then I use Harrisons.
But wouldnt really use it for comprehensive step 2ck preparation. Just as reference if something isnt clear.
And i do not own the MCQ book, I have enough to do with finishing Kaplan Q Bank and UW Q Bank till my exam date
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