usmle262005
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A 3-year-old boy has had intermittent headache and exophthalmos for 6 months and chronically infected ears
and nocturia for 3 months. Examination shows fluid draining from both ears. X-ray films of the skull show multiple, discrete, lytic bone lesions and bony destruction of the mandible. Which of the following is the most likely diagnosis?
A) Histiocytosis
B) Nutritional rickets
C) Osteogenesis imperfecta
D) Osteosarcoma
E) Thalassemia major
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| frank100
Forum Guru
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histiocytosis class I?
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| study_ing
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interesting one, frank 100 cud u please xplain what the clinic manifestations correspond to?
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| GDS2008
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This is A. Histocytosis
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| mazinger
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Hand Schuller Christians (sorry for the spelling) dz... histiocytosis..
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original mazinger z
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| study_ing
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i agree with the answer..intermitent headche and protruding eyes--> i ve read as a manifestation of the disease...
nocturia---> DI may occur in the disease
was wondering abt the otitis as i hadnt read abt it...is it a maniesation of the disease or a distractor?
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| study_ing
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hey it is due to direct involvement of the ear...here's a simple link which gives the s/s
http://www.cancerbackup.org.uk/Cancertype/Childrenscancers/Typesofchildrenscancers/Langerhanscellhistiocytocis#2238
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