meg
Forum Guru
Topics: 62
Posts: 806
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does Carbon monoxide shift the Hb-O2 dissociation curve?
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| guesttt
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yes, CO shift the curve to the left and decrease the O2 carrying capcity of the Hb, thus the curve bend downward. So, the curve turn left and bend downward.
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| meg
Forum Guru
Topics: 62
Posts: 806
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that is what I thought, but I read in Step up (Samir Mehta) that CO does not cause any change ::very_confused::
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| guesttt
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i don't have that text, but i do notice that sometimes, different book say different things, i confirm that with Physio by Costanso.
Like in Micro/ immuno. Kaplan, mixed up the Light and Heavy chain on the Ig labeling! it was so confusing!!
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| dr.sid
Forum Newbie
Topics: 1
Posts: 7
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u r right guest co poisoning shifts the curve to the left and downwards it becomes flatter and carrying capacity is reduced
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| Idiopathic
Forum Guru
Topics: 19
Posts: 641
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You might be thinking of CN...cyanide does not affect the O2 curve, although both CO and CN inhibit cytochrome oxidase.
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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I agee with Dr.sid
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