drpkaur
Forum Guru
Topics: 195
Posts: 808
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HI GUYS
I WAS SURFING ALONG N FOUND THESE NEWER DRUGS THAT R BEING TESTED IN VARIOUS EXAMS CHK THEM OUT
2005
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Exenatide: For the adjunctive treatment of Type 2 diabetes mellitus
Mecasermin: For the treatment of growth failure due to Primary IGFD
Pramlintide: For the treatment of type I and type II diabetes
Tipranavir: For the adjunctive treatment of HIV-1 infections
Entecavir: For the treatment of chronic hepatitis B infections with evidence of active viral replication
Ibandronate: For the treatment and prevention of osteoporosis
Galsulfase: For the treatment of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)
Ramelteon: For the treatment of sleep-onset insomnia
Natalizumab: For the treatment of relapsing forms of multiple sclerosis
Nelarabine: For the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma
2004
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Bevacizumab: For the treatment of metastatic carcinoma of the colon or rectum
Cetuximab: For the treatment of EGFR-expressing, metastatic colorectal cancer
Azacitidine: For the treatment of several myelodysplastic syndrome subtypes including refractory and chronic myelomonocytic leukemias
Telithromycin: For the treatment of infections caused by bronchitis, bacterial sinusitis and Community-acquired pneumonia
Rifaximin: For the treatment of Travelers' diarrhea caused by noninvasive strains of Escherichia coli
Fosrenol, lanthanum carbonate; For the treatment of hyperphosphatemia related to kidney dysfunction
Trospium chloride: For the treatment of overactive bladder with symptoms of urge urinary incontinence
Cinacalcet: For the treatment of secondary hyperparathyroidism and hypercalcemia in parathyroid carcinoma patients
Solifenacin succinate: For the treatment of overactive bladder with symptoms of urge urinary incontinence
Eszopiclone: For the treatment of insomnia and sleep maintenance
Natalizumab: For the treatment of relapsing forms of multiple sclerosis (currently suspended in US)
clofarabine: For the treatment of acute lymphoblastic leukemia in pediatric patients
Erlotinib, OSI 774: For the treatment of advanced refractory metastatic non-small cell lung cancer
Pegaptanib: For the treatment of wet age-related macular degeneration
Duloxetine: For the treatment of major depressive disorder
Tiotropium bromide: For the treatment of bronchospasm associated with chronic obstructive pulmonary disease
2003
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Rosuvastatin calcium: For the treatment of primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia
Vardenafil: For the treatment of erectile dysfunction related to sexual activity in men
Alefacept: For moderate to severe chronic plaque psoriasis
Laronidase: For the treatment of Mucopolysaccharidosis I (MPS I) in subjects aged 5 to 65
Agalsidase beta: For the treatment of Fabry disease in adult patients
Pegvisomant: Injectable formulation for the treatment of acromegaly
Palonosetron: For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
Aprepitant: For the treatment of nausea and vomiting associated with chemotherapy
Bexxar; For the treatment of patients with CD20 positive, follicular, non-Hodgkin's lymphoma following chemotherapy relapse
Atazanavir sulfate: For the treatment of HIV-1 infection in combination with other antiretroviral agents
Zemaira (alpha1-proteinase inhibitor: For the treatment of alpha1-proteinase inhibitor deficiency (Alpha-1) and emphysema
Enfuvirtide: For the treatment of HIV-1 infection in combination with other antiretroviral agents
Fosamprenavir calcium: For the treatment of HIV infection in adults in combination with other antiretroviral agents
Atazanavir sulfate: For the treatment of HIV-1 infection in combination with other antiretroviral agents
Laronidase: For the treatment of Mucopolysaccharidosis I (MPS I) in subjects aged 5 to 65
Ibandronate: For the treatment and prevention of osteoporosis
Pegvisomant: Injectable formulation for the treatment of acromegaly
Bortezomib: Injectable agent for the treatment of multiple myeloma patients who have received at least two prior therapies
Agalsidase beta: For the treatment of Fabry disease in adult patients
Tadalafil: Oral agent for the treatment for erectile dysfunction
Memantine: For the treatment of moderate to severe dementia of the Alzheimer’s type
Palonosetron: For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
Aprepitant: For the treatment of nausea and vomiting associated with chemotherapy
Gefitinib: For the second-line treatment of non-small-cell lung cancer
Bortezomib: Injectable agent for the treatment of multiple myeloma patients who have received at least two prior therapies.
Gefitinib: For the second-line treatment of non-small-cell lung cancer
Anakin-Ra : recombinant TL-1 receptor antagonist used in Rheumatoid Arthritis
Ranolazine & Trimetazidine : Novel anti-anginals, shift myocardial respiration from aerobic to anaerobic
Napsagatran : anti-coagulant
Aprepitant : Neurokinin1 receptor antagonist used to treat Chemotherapy induced nausea & vomiting
Azacitidine : Used in treatment of Myelodysplastic syndrome
Levosemendan : Calcium channel sensitizer used in CHF
Cromakalim : Potassium channel opener having 'NO' donating properties
Argatroban : Direct thrombin inhibitor
Exemestene : Aromatase inhibitor
Dexmedetomidine : used in de-addiction
Gefitinib : Treatment of Lung Cancer
Miltefosine : Visceral leishmaniasis
Verteporfin : Photodynamic therapy
SOME HIGH YIELD DRUGS SIDE EFFECTS
Protease Inhibitors (in general)= hyperglycemia, hyperlipidemia
(lipodystrophy)
Cisapride = Torsade
Methotrexate (long-term use)= liver fibrosis, folate deficiency
anemia
Asparaginase = pancreatitis
NITROFURANTOIN----------- CHRONIC HEPATITIS AND PULMONARY FIBROSIS
AZATHIOPRINE---------------CHOLESTASIS
OCP----------------------------HEPATIC ADENOMA
------------------------------------------------------------------------- -------
didanosine--dose dependent pancreatitis, painful peripheral neuropathy, diarrhoea, hyperuricemia, optic neuritis.
Aspirin = ototoxicity and respiratory alkalosis/metabolic acidosis
(mixed)
Quinidine = diarrhea, thrombocytopenia
Acarbose = flatuence, GI distress
Methimazole = agranlocytosis, aplastic anemia
Prazosin = First-dose syncope (give the first dose in your office
Ethosuximide = GI upset
Tolcapone = Hepatotoxicity
Thioridazine = retinal deposits, Torsade
Vancomycin = "Red Man" Syndrome
Chloramphenicol= "Gray Baby" Syndrome
Cimetidine = Gynecomastia
Ketoconazole = Gynecomastia
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thioglitazone, tacrine - hepato toxicity
etomidate- adrenal suppression
chloroform, ether- hyperglycemia
nicotinic acid- icthyosis
calcium agonists- constipation!!!
azathioprine, valproate, l-asparaginase, thiazides-pancreatitis
zdv- hypochromic, megaloblastic anemia
proton pump inhibitors- redistribution of fat, hyper glycemia
outdated tetracyclines, nalidixic acid- pseudo tumour cerebri
A Quick Contra-Indications list to common drugsContraindications to Use of Antimalarials
* Allergy to 4-aminoquinoline derivatives
* Retinopathy or visual field deterioration
Contraindications to Use of Anti-Tumor Necrosis Factor (Anti-TNF) Agents
* Sepsis or clinically manifest infections and/or abscesses
* Past medical history of hypersensitivity to infliximab or other murine proteins
Contraindications to Use of Azathioprine
* Known neoplastic disease
Contraindications to Use of Cyclophosphamide
* Pregnancy
* Chronic or active infection
* Liver disease
* History of neoplasia
* Renal failure is a relative contraindication that requires adjustment of dosage.
Contraindications to Use of Cyclosporin A
* Coexisting cancer (except non-melanoma skin cancer)
* Uncontrolled hypertension
* Renal dysfunction
* Uncontrolled infections
* Primary and secondary immunodeficiency
Contraindications to Use of D-penicillamine
* Kidney disease
* Blood disorders (e.g., leukopenia, thrombocytopenia)
Contraindications to Use of Leflunomide
* Serious immunodeficiency
* Dysplasias
* Uncontrolled infection (due to the theoretical possibility of immunosuppression)
* Moderate or severe renal failure (there is no experience in this group of patients)
* Liver function disorder
* Significant bone marrow disorder
* Severe hypoproteinemia
Contraindications to Use of Methotrexate
Absolute contraindications
* Pregnancy
* Alcohol abuse
* Hepatitis B or C
* Cirrhosis of any origin
Relative contraindications
* Renal failure
* Chronic pulmonary disease
* Active infection not associated with Felty’s syndrome
Contraindications for Use of Gold Salts
* Severe liver or kidney disease
* Blood and marrow disorders
Contraindications for Use of Sulphasalazine
* Allergy to salicylates or sulfonamides
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| Ivil
Forum Senior
Topics: 8
Posts: 169
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Thanks a lot Drpkaur. I was thinking of compiling that list. You made it easy for me.
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Even if you are on the right track, you will get run over if you just sit there...KEEP RUNNING
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