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Kaplan Qbank USMLE



Author4 Posts
  #1



  #2

If you answer, explain, otherwise don't please.

  #3

a- acetoacetate-- starvation cause ketoacidosis, we have imbalance in carbohydrate and fat metabolism- the enzyme HMG CoA lyase gets us acetone breath, aceetoacetate and betahydroxybutyrate... Your right Musq- in a forumlike this its the EXPLANATION that many dont give which is IMPORTANT!!. [I agree with that philosophy, there is no free lunch] By the way your a good fighter.//some will be scared toanswer your qs but its ok. [I think a dipstick only measures acetoacetate][ this is a high anion gap ketoacidosis]

alanine shoud be the same or lowered. glucose, chylomicron and HCO3 should be decreased.

{Ill return}



Edited by mjl1717 on 07/25/06 - 08:03 AM

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  #4

A) Acetoacetic Acid RIGHT ANSWER

Long term starvation induces many biochemical changes. Much of the body's energy requirements are normally supplied by serum glucose, but in starvation are supplied by both glucose and lipid-derived ketone bodies, including acetoacid acid and beta-hydroxybutiric acid. Glucose cant be sx from lipids, and is instead made from aa such as ALANINE in the process of Gluconeogenesis.

B) Alanine, drops dramatically in starvation due to its convertion to glucose

C) Bicarbonate levels drop as the HCO3 buffers the H ions produced by ketone bodies

D) Chylomicrons are the lipid form seen after absorption of dietary fat, and would drop because the person is not feeding

e)Glucose is maintained in the blood at a much lower than normal level during starvation










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