mitty
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A 9-year-old girl has pallor and splenomegaly. Her medical records indicate that as a newborn she had jaundice severe enough to require exchange transfusion. Blood films show that about 50% of her blood cells are small, deeply stained, and spherical. The most likely cause of these findings is a defect in which of the following molecules?
a Ankyrin
b Decay accelerating factor
c desmin
d dystrophin
e fibrilin
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| tolito
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by elimination i choose A.
She has cong spherocytosis
b. causes PNH
c. desmin is in muscle and is a marker for sarcoma. maybe defect causes cardiomyopathy
d. causes muscular dystrophy
e. causes marfans
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| raves
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defect in either ankyrin or spectrin can result in spherocytosis.
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| robin082006
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A
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| mitty
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yes A
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| sridevibandaru24
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A
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