mjl1717
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Ill go with answer-a- citrate synthase/////as far as b -he's already getting glucose and carbos, so he doesnt need to make glucose from non carbohydrate precursors.
**Most significant- he's making a heck of lot of ATP's
Edited by mjl1717 on 07/23/06 - 06:44 PM
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| robin082006
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A
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| mjl1717
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a-citrate synthase is a pacemaker enzyme to start Krebs cycle
b- I mentioned above
c- take you from AcetylacetylCoa to HMG CoA
d- lipoprotein lipase cleaves one FA from triacylglycerol in chylomicrons in endothelial cells
e-ornithine transcarbamylase is second enzyme in urea cycle {I forgot the actual detail}
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| mjl1717
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But in real life he'd be started on Normal IV saline with insulin and a trace of potassium assuming his glucose was 800 or 900 mg/dl? And Thiamine!/ Naloxone? {monitoring input and output and doing frequent finger sticks} Is this correct or am I losing my mind at this point??? Also Nursing should be sued for giving the wrong diet.
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| mitty
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ok mj, this is the explanation given.
Option D (Lipoprotein lipase) is correct. Lipoprotein lipase is increased by insulin, which would rise rapidly after refeeding following a fast. The excess carbohydrate is converted into triglycerides.
Option A (Citrate synthase) is incorrect. Citrate synthase is already increased to metabolize the acetyl CoA from fatty acid oxidation.
Option B (Glucose-6-phosphatase) is incorrect. Glucose-6-phosphatase is already increased to release glucose produced in gluconeogenesis from the liver.
Option C (Hydroxymethylglutaryl (HMG)-CoA synthase) is incorrect. To adapt to starvation, HMG-CoA synthase, the enzyme catalyzing the rate limiting-step in ketogenesis, is already maximally increased to form ketone bodies.
Option E (Ornithine transcarbamoylase) is incorrect. Ornithine transcarbamoylase is already increased to dispose of amino acid nitrogen in the urea cycle.
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| study_ing
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vow good one mitty thanx
frequently overlooked point !!!
TCA cycle aint regulated by hormones...glycolysis is!!
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| mjl1717
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Very good q mitty- In the backof my mind Im saying "Doesnt ketone production mean there is an imbalance in fat and carbohydrate metabolism?"
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| Musuq
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thanks for the review
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