OSTEOPOROSIS

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OSTEOPOROSIS

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suv
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07/20/06 - 07:11 PM

A 52-year-old woman presents to her physician for a check-up. She is recovering from a wrist fracture after a fall. Dual energy x-ray absorptiometry of the hip had shown her to have osteoporosis. She became menopausal at age 50 and did not begin hormone replacement therapy because of a strong family history of breast cancer. She now fears a future hip fracture and would like to begin a bone loss prevention regime.Which of the following pharmaceutical agents is most appropriate for this patient?

A. Calcitonin nasal spray
B. Oral conjugated estrogen
C. Raloxifene
D. Tamoxifen
E. Transdermal estradiol

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robin082006
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07/20/06 - 07:42 PM

C

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DrVirgo
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07/20/06 - 07:47 PM

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mjl1717
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07/20/06 - 08:16 PM

Id tell her# 1)1200 mg Ca++& trace magnesium #2) 1000 I.U. Vitamin D #3)weight bearing exercise (not swimming) and bone stabilizer like (Fosamax) alendronate. As far as I know Tamoxifene is an antiestrogen used after estrogen sensitive breast Ca surgery

addendum-it was only as of April 2006 that raloxifene was found to be as good as tamoxifene in decreasing breast ca/we know of the osteoporosis part.. How do you like these big time side effects- chest pain, trouble breathing, thromboembolic events, that enough? How about stroke and cataracts also??

**As far asI know it must be "ESTROGEN SENSITIVE" breast ca for raloxifene to be effective.

Edited by mjl1717 on 07/20/06 - 09:50 PM

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suv
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07/20/06 - 09:31 PM

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mjl1717
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07/25/06 - 06:50 AM

Sorry,,but Fosamax got some bad press in last 24 hrs?

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ts97
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07/25/06 - 07:57 AM

Why not Calcitonin nasal spray? I found that it used in corticosteroid-induced ostoeporosis, but also it is recommended for postmenopausal osteoporosis. I think the clue is that raloxifene will help to prevent breast cancer. When then Calcitonin nasal spray will be used?

sridevibandaru24
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07/25/06 - 10:14 AM

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