 |  To tolito,robin,mj,drvirgo ,study_ing
|
 
|
| Author | 15 Posts |
drpkaur
Forum Guru
Topics: 195
Posts: 808
|
hey guys in lippincott's 3rd edition biochemistry book it's written that acute intermittent porphyria is caused by deficiency of hydroxymethylbilane synthase (hydroxymethylbilane is formed from porphobilinogen) and in kaplan notes it's due to deficiency of uroporphyrinogen I synthase ...which one is correct...
which enzyme deficiency causes congenital erythropoietic porphyria???
|
| study_ing
Forum Fanatic
Topics: 180
Posts: 2,511
|
hydroxymethylbilane (HMB) synthase (also called PBG deaminase)
Erythropoietic porphyria
The erythropoietic porphyrias include:
X-linked sideroblastic anemia (XLSA): a deficiency in ALA synthase
congenital erythropoietic porphyria (CEP): a deficiency in URO synthase
erythropoietic protoporphyria (EPP): a deficiency in ferrochelatase
___________________
If you yourself are at peace, then there is at least some peace in the world.
|
| tolito
Forum Fanatic
Topics: 119
Posts: 2,164
|
thanks for asking this question. if this one comes in the exam, i will give it a TKO!!! i am not the best in bioch but i got this reference
http://www.biochem.ucl.ac.uk/bsm/enzymes/ec4/ec03...
they are the same enzyme.
Porphobilinogen deaminase.
Pre-uroporphyrinogen synthase.
___________________
It has been a looooong hard journey but I am inches away from my destination...
|
| study_ing
Forum Fanatic
Topics: 180
Posts: 2,511
|
the previus post was from my search of the net..
and this is what te Q bank said
Congenital erythropoietic porphyria (low activity of uroporphyrinogen III synthase)
___________________
If you yourself are at peace, then there is at least some peace in the world.
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,125
|
thank study-ing and tolito
___________________
The Key to Succeed is Patience.
|
| drpkaur
Forum Guru
Topics: 195
Posts: 808
|
Thanx guys for your gr8 input....gr8 buddies to have like u people on this forum....
|
| DrVirgo
Forum Hero
Topics: 1084
Posts: 3,472
|
If any doubt, go with Kaplan
If Goljan an Kaplan doubt, go with Goljan.
Never FA. 
Sorry, I just saw your Q.
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
Was moving to a new apartment sorry I could not contribute. As with "Porphyria cutaneous tarda" Im "OUT OF THE LIGHT" with this one. *key words- Uroporphyrinogen decarboxylase, blister, phlebotomy, a little chloroquine. Was taught by grandfather its better to say something even boo! rather then say nothing at all.
*you guys did good job!
Edited by mjl1717 on 07/20/06 - 09:33 PM
___________________
Smell the coffee! "Is That an Osler move??"
|
| tolito
Forum Fanatic
Topics: 119
Posts: 2,164
|
MJ, your grandpappy must be a very interesting man.. boo!!!! ( now i can understand why you dont like people who dont contribute much :
___________________
It has been a looooong hard journey but I am inches away from my destination...
|
| mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
I respect what you're saying. Its just that {in my opinion} in medicine the art of good communication {which many will take for granted} is 50% of the battle {even with the exams).
[Some struggle to communicate properly even in there own indigenous country!] But Ill tone it down.
___________________
Smell the coffee! "Is That an Osler move??"
|
| mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
Those porphyrias are like "another can of worms" to master.
___________________
Smell the coffee! "Is That an Osler move??"
|
| study_ing
Forum Fanatic
Topics: 180
Posts: 2,511
|
http://www.prep4usmle.com/forum/comments.php?id=6...
source of mnemonic
very comprehensive
___________________
If you yourself are at peace, then there is at least some peace in the world.
|
| study_ing
Forum Fanatic
Topics: 180
Posts: 2,511
|
2 important porphyreas..
AIP and pCT
difference in clinical presentation
Pct is Photosensitive.
___________________
If you yourself are at peace, then there is at least some peace in the world.
|
| tolito
Forum Fanatic
Topics: 119
Posts: 2,164
|
good one study-ing
___________________
It has been a looooong hard journey but I am inches away from my destination...
|
| mjl1717
Forum Hero
Topics: 955
Posts: 5,451
|
Good studying-we must start somewhere! PCT is most common.
___________________
Smell the coffee! "Is That an Osler move??"
|
|
| |
| | | | | | | | | | | | | | | |
You don't have permission to post.
|
