Musuq
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In the family represented by the pedigree, affected persons have a disease characterized by mitochondrially inherited late-onset optic atrophy. Assuming that the family and personal medical history of the partner is unremarkable, the risk for optic atrophy to develop in the male child of IV-9 is closest to
A ) 0%
B ) 25%
C ) 50%
D ) 75%
E ) 100%
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| plastic_girl
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E......?
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| study_ing
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and where's the pedigre...btw i think this has been discussed too. it was 0% i think coz i think IV -9 was a guy and they dont transmit mitochondrial diseases
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| robin082006
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A
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| plastic_girl
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Damn!! ..........sigh.......back to it then.........
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| muzammil
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a definitly
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| Musuq
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thanks study_ing, you always give real answers
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| study_ing
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| Allison
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I think the answer is 100% they are asking the risk for optic atrophy to develop in the male child of IV-9 is closest to ? they are talking about this child.
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| ola_godin
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e
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| NE
Forum Guru
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Guys, a child of a male with a mitochondrial inherited disease has 0% risk of the disease because the spermatozoa lost the mitochondria just before oocyte's penetration.The mitochondrial DNA is maternal!
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| drfax
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The answer is A. 0%
at first I choosed E. too, but when looking at the stem of the Q you will find the statement "Assuming that the family and personal medical history of the partner is unremarkable" they mean the partner of the male IV-9 which is important in determining the disease.
Good luck to all
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| Diego Casali
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It's A for sure: only females can transmit a mitochondrial disease.
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| ashfaque
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A
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