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Kaplan Qbank USMLE



Author8 Posts
  #1

Actively dividing fibroblasts in culture are transferred from a 37 C incubator to a 0 C ice bath, and 10-6 M colchicine is added to the culture medium. After 30 minutes, many cells have been arrested in mitosis. Which of the following cytoskeletal proteins is most likely to be involved?<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

A) Actin

B) Desmin

C) Dynein

D) Keratin

E) Kinesin

F) Lamins

G) Myosin

H) Neurofilament proteins

I ) Tubulin


Edited by Musuq on 07/19/06 - 11:26 PM

  #2

I

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  #3

i tubulin

  #4

nod

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  #5

why?




  #6

the clue is 'arrested in mitosis'..u have to chose a protein which stops spindle formation and tubulin is involved..others are mainly cytoskeleton proteins in general (lamin wud be the other choice)
the mechanism of colcichine involves tubuli

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  #7

thanks grin




  #8

I

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