DrVirgo
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Does anyone have an easy way to remember all the interleukins???
They are driving me crazy!!!
---I know HOT T-Bone stEAk mnemonic from FA, but I believe we have to know a lot more detail than that simple mnemonic!!!
Lets go over them...
IL-1:
-Produced by Mac... goes to T and B...stimulates IL-2... Fever inducer
(anything else)??
Does anyone want to continue the list?? 
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| drpkaur
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hi here is some information regarding interleukins..hope it helps..
Attached Files:
Types And Functions Of InterLeukins In The Immune System.htm (23 KB, 77 downloads)
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| study_ing
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lets do qs to help u learn..bare minimum first
1. which one is chemotactic?
2. which one for IgA
3.. for Ig E
4.INhibits TH 1 pathway
5. CMI imp...
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| DrVirgo
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Is this a PDF? What do i open it with?
drpkaur wrote:
hi here is some information regarding interleukins..hope it helps..
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| robin082006
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1. which one is chemotactic? : IL8, Leucotriene B4, C5a
2. which one for IgA: IL5
3.. for Ig E: IL4
4.INhibits TH 1 pathway: IL10, IL4
5. CMI imp...
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| DrVirgo
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1. IL-8 is chemotactic to neutrophils
2. IL-5 stimulates IgA production
3. IL-4 for Class switching B-cell from IgM to IgE (e.g. Hypersensitivity Type I)
4 and 5 not sure without cheating to look up... 
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| DrVirgo
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I'll continue tomorrow...
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| tolito
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1. il 8
2. il 5
3. il 4
4. il 4,10
5. il 1, 2, 12
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| tolito
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6. inhibits Macrophage strongly
7. synth in response to int worms
8. b cell differentiation factor
9. lack of it leads to t cell clonal anergy
10. is osteoclast activatiing factor
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| khorshid
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6. IL10
7.IL 4
9. IL2
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| DrVirgo
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I think
10. Osteoclast activating factor is IL-1.
Right?
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| study_ing
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hey great response..
lets do qs to help u learn..bare minimum first
1. which one is chemotactic? IL 8
2. which one for IgA ? IL 5
3.. for Ig E ? IL 4
4.INhibits TH 1 pathway --IL 10
5. CMI imp...IL 12
i have listed one only on purpose coz i wanna give u the most significant ones..
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| study_ing
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just deleted my post coz it wud coz confusin!!
Edited by study_ing on 07/20/06 - 02:08 PM
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| study_ing
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11. name two important 'endogenous pyrogens'
12. now the not very imp but hematopoietic IL 3 is left ( was unfair to ask as a Q coz i thinks lots are hematopoietic)
well ...lets post any remaining ones and we'll move on to the FACTORS ( TGF etc) and IFNs
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| tolito
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6. inhibits Macrophage strongly IL 4 ( il 10 also inhibits macrophage but 4 is said to do so strongly)
7. synth in response to int worms IL 5 (this causes eosinophilia)
8. b cell differentiation factor IL 5
9. lack of it leads to t cell clonal anergy IL 2
10. is osteoclast activatiing factor IL 1
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| tolito
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11. il 1, il 6
12, stimulates myeloid cell line ( see 3 as sideways m, see 7 as upside down L for lymphocyte line)
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| study_ing
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good job !!
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| study_ing
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tolito the pg dr pkaur posted says
InterLeukin-3 (IL-3)
Produced by activated T-Cells, it stimulates the proliferation of Precursors in all HematoPoietic Cells (Red Cells, Granulocytes, Macrophages, and Lymphocytes).
InterLeukin-7 (IL-7)
Is made by Bone Marrow Stroma Cells and acts on Thymocytes. IL-7 is a T-Cell growth and activation factor, and a Macrophage Activation Factor.
im sure its got many axns and hence wont b important!!
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| truedeam59
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The attached file is in explorer not PDF
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