asmi
Forum Hero
Topics: 1043
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Can anybody tell about HIV vaccines ?
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| meg
Forum Guru
Topics: 62
Posts: 806
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I dont think any are out in the market. The HIV virus like the influenza keeps evading due to mutations.
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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I meant they are trying to reach a vaccine(research going on), but the mutations especially of envelope glycoprotein antigens(V3 loop etc) is hampering it.Highest mutation rate seen with pol gene.
Anyways they r trying with recombinant HIV-1 envelope glycoprotein vaccine, soluble CD4 recptors, using live recombinant organisms.
over all still not yet accomplished in developing a good vaccine.
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| meg
Forum Guru
Topics: 62
Posts: 806
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Asmi, please tell me the book/material you are referring for this. I should read it, HIV is important for boards :shock:
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| asmi
Forum Hero
Topics: 1043
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meg I read this from made rediculously simple.
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| meg
Forum Guru
Topics: 62
Posts: 806
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thanks, will try to get it and read that section on HIV
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| Guavero
Forum Newbie
Topics: 0
Posts: 1
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Hey,
I know a little about HIV vaccines. I think that most vaccines that were developed before was towards mounting an antibody response. These failed mainly because HIV has been able to evade the Ab since it's an intracellular pathogen. Therefore, people have looked into a new breed of vaccines dealing with a cell mediated immune response CD8+. However, scientist who are conducting research on this field are once again saying that a cell mediated response alone is not potent enough and might need to make a vaccine with both CD4 and CD8 characteristics.
I hope I didn't confuse anyone. Anywayz, this is my first post in this forum. I hope we will all do great on the boards 
Guavero
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