mjl1717 Forum Hero

Topics: 960 Posts: 5,468
| | 01/19/04 - 06:46 PM  
 
|   #2 |
INTRAVASUCLAR volume contraction increases ADH secretion,overriding the effect of hyposmolarity
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| leftfoot Forum Elite
Topics: 29 Posts: 216
| | 01/19/04 - 07:06 PM  
 
|   #3 |
thanks mjl...... but ,how does that help the patient as the increase in ADH wont do anything coz in this condition the collecting ducts are unresponsive to ADH....... :?
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| mjl1717 Forum Hero

Topics: 960 Posts: 5,468
| | 01/19/04 - 07:32 PM  
 
|   #4 |
you are right -HYDRATION (ADH does nothing) **Thiazide decreases urine flow by inhibiting sodium reabsorption in distal tubule**This lowers free water production and, by causing extracelular volume contraction,increases proximal salt and water reabsorption,reducing delivery to the distal nephron. :idea:
___________________ Smell the coffee! "Is That an Osler move??"
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| leftfoot Forum Elite
Topics: 29 Posts: 216
| | 01/19/04 - 07:48 PM  
 
|   #5 |
:idea: thanks mjl!!! 
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