Musuq
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Eukaryotic proteins that exist as a nonmembrane-associated, glycosylated, disulfide-linked dimer in the mature form are generally found in which of the following?<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />
A) Cytoplasm
B) Extracellular space
C) Mitochondrial matrix
D) Nuclear matrix
E) Nuclear pore
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| plastic_girl
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D - Nuclear matrix?....
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| star1
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B extracellular space
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| raves
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| pallav
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boy these q are
shaking the hell out of me
what should i do
shd i quit mle
]and go and become a nomad in the himalayas
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| new_n_lost
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the ans plz with explanation would help
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| study_ing
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any one ?
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| keepgoing
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EXTRACELLULAR SPACE
very well explained by Drvirgo in his post...
Here's what happens:
Proteins are either made on Free Ribosomes or on Ribosomes associated with the Endoplasmic reticulum: RER.
Proteins made on Free ribosomes are targeted to the cytoplasm, and mitochondria.
Proteins that are made in the RER undergo post-translational modification and get glycosylated in the RER as well as the Golgi and go to:
1. Extracellular space (get secretd out of the cell)
2. Become a membrane protein (within the membrane like a channel, etc.)
3. Lysosomes (eg. Lysosomal enzymes)
* (Lysosomal enzymes will only go to Lysosomes if there is phosphorylation of mannose residues on the enzyme that takes place in the Golgi!) -If NO phospyorylation of mannose residues, then that enzyme gets secreted out of the cell! (I-Cell Disease)
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| study_ing
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thanx keepgoing...good job
the forum has so many posts its dif to keep track
thanx for posting the answer
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| vamsi2004
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the ans is extracellular space but the reason given by keepgoing does not correlate to this ques. this q is about antibodies (disulfide linked). they are always extracellular..
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