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Kaplan Qbank USMLE



Author19 Posts
  #1

When a cytogenic abnormality is suspected in an infact with multiple congenital anomalies chromosomes from leukocytes are analyzed
these chromosomes are most condensed and easiest to evaluate in which of the following states ?

a.-anaphase
b.-interphase
c.-metaphase
d.-prophase
e.-telophase

  #2

sticking out tongue

  #3

c

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  #4

Thanks

C

your turn

  #5

I Thought it was prophase

  #6

C

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  #7

Remember the "metaphase spread"

Its when the spread out all the chromosomes so you can visualize them.

http://images.google.com/imgres?imgurl=http://www...

http://images.google.com/imgres?imgurl=http://www...


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  #8

Hi sorry i dont agree here if i m not wrong ans shud be "D"

PROPHASE ----remember"Chromatin in the nucleus begins to condense and becomes visible in the light microscope as chromosomes. The nucleolus disappears. Centrioles begin moving to opposite ends of the cell and fibers extend from the centromeres. Some fibers cross the cell to form the mitotic spindle"

whereas
in METAPHASE---"Spindle fibers align the chromosomes along the middle of the cell nucleus. This line is referred to as the metaphase plate. This organization helps to ensure that in the next phase, when the chromosomes are separated, each new nucleus will receive one copy of each chromosome"

do excuse me if i didnt understand the question and in that case plz explain...???

thanx

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"Deh Shiva Var Mohe Ahey ,Shubh Karman Te Kabhun Na Tarun ,Na Darun Arson Jab Jaye Laroon, Nischey Kar Apni Jeet Karoon"

  #9

i wonder....(after re-reading the question)....whether it shud be PROPHASE OR METAPHASE?now it seems METAPHASE to me raised eyebrow

but its really confusing wen at the end of question stem----" MOST CONDENSED"(which is seen only in PROPHASE)and 2nd "EASY TO EVALUATE"(WHICH IN THIS CASE BEST CAN be EVALUTED DURING "METAPHASE) is simultaneously given...........................than what we should consider while attempting an ANSWER????
is there anyone who can help me out here???it seems i get easly confused or i make things confusing NOT GUD thing...rolling eyes

i will appreciate ur comments friends....plz CEDRICK or DRVIRGO help me....sad

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"Deh Shiva Var Mohe Ahey ,Shubh Karman Te Kabhun Na Tarun ,Na Darun Arson Jab Jaye Laroon, Nischey Kar Apni Jeet Karoon"

  #10

C- Metaphase

one other site to convince keep going
http://www.pathology.washington.edu/galleries/Cyt...


  #11

Interphase.-Go-S-G1-G2 cell cycle

Mitosis.-prophase
.-prometaphase
.-metaphase
.-anaphase
.-telophase

That is the correct order for the phases of cell cycle
.-cytokinesis


  #12

Prohase.-chromatin CONDENSES to from a well defined chromosomes
.-centrosomes move to the opposite poles
.-mitotic splindle"microtubuoles" form between the centromeres

Prometaphase.-nuclear envelope is disrupted
.-nucleolus disappears

Metaphase.-chromosomes Align
.-can isolated for karyotype analysis

Anaphase.-chromosomes move to opposites poles
Telophase.-chromosomes Decondense to form chromatin
Cytokinesis.-Cytoplasm divides by cleavege



  #13

in this question the distractor is most condensed vs align,I think that is were one can get confused
hope that this helps "Keepgoing"

thanks for the PM

  #14

oops my reference is "High-Yield Histology"
second edition
page 10,table 1-6,phases of cell cycle

  #15

Thank you so much... spjokes and cedrick!
@spjokes--thank u really nice link!

@Cedrick---thank u so much raelly u have made my query very simple and an answering to it easier for me and rt these distracters are aweful but a very tricky question...!

regards,

___________________
"Deh Shiva Var Mohe Ahey ,Shubh Karman Te Kabhun Na Tarun ,Na Darun Arson Jab Jaye Laroon, Nischey Kar Apni Jeet Karoon"

  #16

your wellcome

  #17

d.-Prophase

the question is condensed an easy to evaluate



  #18

i agree its prophase

  #19

hope that we can review







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