Cedrick
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Collapse of the histologic architecture of hepatocyte
a.-decreased intestinal motility
b.-gallstones
c.-increased central venous pressure
d.-increased hepatic venous pressure
e.-increased portal pressure
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| study_ing
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a, b and e ae not causes of cirrhosis.
im confused btw C and D.
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| Cedrick
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so we agre that there is cirrhosis
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| Cedrick
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now lets search on this one
maybe Portal pressure ?
E ?
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| star1
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Did you noticed fibrosis in the Q stem.. its cirrhosis and so the portal pressure will be high
E 
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| Cedrick
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thanks Professor
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| Cedrick
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Thanks Star 1
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| star1
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hahahah me professor ...........
Do you know this picture is of our Great professor Dr. Goljan Edward...
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| study_ing
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well the question asks what wud cause the histology to develop in such a way. portal HTN is a result of, not a cause of it.
btw our dear professor has stressed on this point...(the real one, that is)
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| Cedrick
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yes I know the Photo of a great ,wise and generous teacher
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| study_ing
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unfortunately C or D remains a matter of confusion...
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| mjl1717
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im guessing portal pressure
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| waqastariq
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is this complete question?
Collapse of the histologic architecture of hepatocyte
a.-decreased intestinal motility
b.-gallstones
c.-increased central venous pressure
d.-increased hepatic venous pressure
e.-increased portal pressure
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| waqastariq
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collapse of architecture causes the BM to fall too..thats what I know and then there is increased portal pressure...
because HEPATIC VENOUS PRESSURE is almost the same as in Inferior vena cava...as they drain into it.... 
others dun look like one
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| study_ing
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i am so sorry. i cam e across the question again and realised i was making the exact mistake i h was warning ppl about!!
the question asks what the result of the distortion is. so its elevated portal pressure for sure
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| tolito
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if the question asks about consequence of distorted architecture, answer would be increased portal pressure but if it asks about what causes the distortion then increase in CVP will be right ( from right heart failure----nutmeg liver, cardiac cirhosis)
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| muzammil
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the consequence of cirhosisi incresed portal pressure i totally agree
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| cdkant
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liver's "zone 1" (around the hepatic vein) is most sensitive to damage (remember goljan acetaminophen toxicity also rhf&nutmeg liver) so i think it is due to incrased cvp, it is either c or d.
(also i recall goljan ruling out portal vein because liver has dual blood supply, if portal vein is screwed hepatic artery will do just fine. )
in actual exam i'd choose hepatic vein.
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