Cedrick
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A 25 year old man swallows 100ml of carbon tetrachloride in a suicide attempt
which of the following is the most likely outcome ?
a.-central nervous system failure as a consequence of DNA damage in neurons
b.-gastric toxicity related to erosive gastritis
c.-heart failure as a result of lipid peroxidation of cardiac myocytes
d.-no toxicity because the kidneys will excrete the carbon tetrachloride
e.-severe hepatoxicity as a consequence of damage to the plasma membranes
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| robin082006
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E
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| Cedrick
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at least I am not the only one alive
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| Cedrick
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Yes
E
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| star1
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CCL4 is converted to CCL3 leading to Liver cell necrosis with fatty change.
what is the common source of CCL4?
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| study_ing
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dunno
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| raves
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is it coal tar??
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| pallav
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e is the answer
but
star whats the source
i think its the material used for drycleaning?
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| Musuq
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Hepatotoxicity is the major effect of exposure to carbon tetrachloride by any route in humans and animals and is the basis for all MRLs derived for that compound.
Liver injury is detectable by clinical signs (jaundice, swollen and tender liver), biochemical alterations (elevated levels of hepatic enzymes in the blood, loss of enzymatic activities in the liver), or histological examination (fatty degeneration and necrosis of central hepatocytes, destruction of intracellular organelles, fibrosis, cirrhosis).
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| ManuNastai
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CCl4 is used in dry cleaning, I think
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| microsatellite
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 Hepatotoxicity is the possible answer to ur question
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| drfax
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Hepatotoxicity is the answer
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| myba
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Used to be widely used as a dry cleaning solvent, as a refrigerant, and in fire extinguishers - not anymore. (from wiki)
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